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. 2020 Nov 12;21(1):36. doi: 10.3892/ol.2020.12297

Table VI.

Association between CD68 or CD204-positive macrophages and clinicopathological parameters or immune subsets.

CD68-positive cells CD204-positive cells


Variables No. Lowa, n Higha, n P-valueb Lowa, n Higha, n P-valueb
HG 0.6055 0.0246
  1-2 48 31 17 33 15
  3 25 18 7 10 15
Ki-67, % 0.8012 0.0152
  ≤20 29 21 9 23 7
  >20 44 28 15 20 23
TILs, % 0.0472 <0.0001
  <10 54 40 14 40 14
  ≥10 19 9 10 3 16
CD3 0.0004 <0.0001
  Low 51 41 10 38 13
  High 22 8 14 5 17
CD8 <0.0001 <0.0001
  Low 54 44 10 40 14
  High 19 5 14 3 16
FOXP3 0.0001 0.0796
  Low 50 41 9 33 17
  High 23 8 15 10 13
CD20 0.0547 0.0706
  Low 59 43 16 38 21
  High 14 6 8 5 9
a

Tumors were categorized into a high or low group based on the mean value of each immune subset.

b

Comparison by Fisher's exact test (2-sided). HG, histological grade; TILs, tumor-infiltrating lymphocytes.