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. 2020 Oct 29;12(11):3326. doi: 10.3390/nu12113326

Figure 2.

Figure 2

Maternal HF diet alters offspring hypothalamic tissue expression of neuropeptides and neuronal phenotype. (A) POMC and AgRP protein expression in hypothalamus of 1-day-old males, and ARC of 12-month-old males from Control (■) and HF (□) groups. Values are fold change (mean ± SE) of n = 6 males from six litters per group (1 male/litter). * p < 0.001 vs Control. (B) ARC sections from representative control (■) and HF (■) 12-month-old males, immunostained for NPY (green) at × 20 and × 100; scale bar = 50 µm. Total NPY (mean ± SE) of n = 6 males from six litters per group (1 male/litter). * p < 0.01 vs control. Abbreviations: HF (high fat); POMC (proopiomelanocortin); AgRP (agouti-related protein); NPY (neuropeptide Y); ARC (arcuate nucleus); 3V (third ventricle).