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. 2020 Nov 26;21:545. doi: 10.1186/s12859-020-03807-9

Table 2.

Performance assessments of direct estimation and multiple imputation for varying number of replicates based on 100 simulated data sets

Direct estimation Multiple imputation
Bias MSE Bias MSE
k=4
θ − 0.024 0.005 0.031 0.112 0.171 0.225 − 0.024 0.004 0.029 0.113 0.170 0.232
σθ2 − 0.002 0.000 0.003 0.001 0.003 0.006 − 0.045 −  0.019 0.030 0.001 0.002 0.005
k=6
θ − 0.024 0.003 0.025 0.072 0.114 0.156 − 0.024 0.003 0.023 0.072 0.114 0.155
σθ2 − 0.001 0.000 0.000 0.000 0.001 0.001 − 0.02 −  0.001 0.014 0.000 0.001 0.004
k=10
θ − 0.014 0.003 0.020 0.044 0.069 0.089 − 0.015 0.002 0.017 0.044 0.069 0.090
σθ2 0.000 0.000 0.001 0.000 0.000 0.000 − 0.008 0.003 0.024 0.000 0.000 0.002

The 25th (left), 50th (center), and 75th (right) quantiles of the bias and MSE are reported