Table 6.
Reproducibility of 3D-speckle-tracking echocardiographic analysis.
| Bland–Altman Analysis [MeanDiff (95% LOA), ICC] | ||||||
|---|---|---|---|---|---|---|
| Intra-observer (n = 20) | Inter-observer (n = 20) | Test-retest (n = 10) | ||||
| Volumetric measures | ||||||
| EDV, ml | −4.6 (−14.3, 5.0) | 0.97 | −1.7 (−11.6, 8.2) | 0.96 | 0.88 (−14.4, 16.2) | 0.85 |
| ESV, ml | −1.1 (−7.1, 4.7) | 0.97 | −1.7 (−7.5, 4.0) | 0.97 | 0.23 (−6.6, 7.0) | 0.85 |
| EF, % | −0.94 (−4.2, 2.3) | 0.96 | 0.79 (−2.5, 4.1) | 0.96 | 0.34 (−2.5, 3.1) | 0.92 |
| SV, ml | −3.4 (−9.6, 2.7) | 0.96 | −0.03 (−6.7, 6.8) | 0.94 | 0.65 (−8.8, 10.1) | 0.87 |
| LV mass, g | 2.1 (−8.7, 13.0) | 0.97 | 1.4 (−15.7, 18.6) | 0.94 | 0.42 (−10.5, 11.3) | 0.96 |
| Deformation measures | ||||||
| GCS, % | 1.19 (−1.0, 3.4) | 0.96 | 0.06 (−2.9, 3.0) | 0.93 | 0.63 (−3.5, 4.7) | 0.79 |
| GLS, % | 0.48 (−1.8, 2.7) | 0.91 | −1.3 (−6.2, 3.4) | 0.60 | −0.84 (−4.8, 3.2) | 0.52 |
| Peak CS, % | 1.03 (−1.5, 3.6) | 0.94 | 0.13 (−3.5, 3.8) | 0.89 | 0.67 (−4.7, 6.0) | 0.64 |
| Peak LS, % | 0.43 (−2.07, 2.9) | 0.88 | −1.5 (−6.1, 2.9) | 0.60 | −1.0 (−5.6, 3.6) | 0.44 |
| Peak PT, % | 1.11 (−1.6, 3.8) | 0.93 | −0.29 (−4.4, 3.8) | 0.84 | 0.2 (−3.1, 3.5) | 0.77 |
| Peak RS, % | −1.22 (−4.2, 1.7) | 0.95 | 1.3 (−4.3, 6.9) | 0.82 | 0.54 (−2.1, 3.1) | 0.87 |
| Rotational measures | ||||||
| Peak basal rotation, ° | 0.10 (−3.3, 3.5) | 0.86 | −0.65 (−5.3, 4.0) | 0.71 | 0.06 (−7.7, 7.8) | 0.35 |
| Peak apical rotation, ° | 0.33 (−5.3, 6.0) | 0.64 | 1.0 (−4.1, 6.1) | 0.69 | 0.65 (−4.1, 5.4) | 0.81 |
| Peak twist, ° | 0.27 (−8.0, 8.6) | 0.73 | 1.7 (−6.9, 10.4) | 0.69 | 0.66 (−9.8, 11.2) | 0.74 |
| Torsion, °/cm | 0.04 (−0.97, 1.07) | 0.73 | 0.22 (−0.88, 1.3) | 0.67 | 0.08 (−1.2, 1.4) | 0.69 |
| Systolic dyssynchrony indices | ||||||
| SDI volume−based, % | 0.10 (−0.30, 0.50) | 0.98 | −0.02 (−0.79, 0.75) | 0.96 | −0.22(−3.2, 2.8) | 0.61 |
| CS SDI, % | 0.11 (−1.9, 2.1) | 0.65 | 0.003 (−1.9, 1.9) | 0.63 | −0.79 (−3.2, 1.6) | 0.72 |
| LS SD, % | 0.08 (−1.5, 1.7) | 0.82 | −0.30 (−1.6, 1.02) | 0.89 | −0.5 (−3.6, 2.5) | 0.82 |
| PTS SDI, % | 0.17 (−0.87, 1.2) | 0.93 | −0.14 (−1.7, 1.4) | 0.83 | −0.2 (−2.8, 2.4) | 0.79 |
| RS SDI, % | 0.22 (−1.06, 1.5) | 0.85 | 0.08 (−1.09, 1.26) | 0.87 | −0.4 (−2.8, 1.9) | 0.81 |
| Di volumes, % | 0.15 (−1.4, 1.7) | 0.95 | −0.30 (−2.2, 1.6) | 0.94 | −0.67 (−10.3, 8.9) | 0.29 |
| CS Di, % | 0.70 (−10.2, 11.6) | 0.15 | 0.31 (−10.1, 10.7) | 0.33 | −2.7 (−17.5, 12.0) | 0.008 |
| LS Di, % | 0.41 (−5.6, 6.4) | 0.80 | −1.3 (−5.9, 3.3) | 0.89 | −2.2 (−10.3, 5.9) | 0.77 |
| PTS Di, % | −0.32 (−5.0, 4.4) | 0.79 | −2.2 (−10.8, 6.3) | 0.47 | 0.54 (−7.3, 8.3) | 0.73 |
| RS Di, % | 0.25 (−4.2, 4.7) | 0.70 | −0.58 (−5.4, 4.3) | 0.73 | −0.74 (−8.3, 6.8) | 0.69 |
Data are mean difference [95% limit of agreement (LOA)]. CS, circumferential strain; Di, dispersion; EDV, end-diastolic volume; ESV, end-systolic volume; EF, ejection fraction; GCS, global circumferential strain; GLS, global longitudinal strain; ICC, intra-class correlation coefficient; LS, longitudinal strain; LV, left ventricular; PTS, principle tangential strain; RS, radial strain; SDI, systolic dyssynchrony index; SV, stroke volume.