Table 2.

C. elegans lipid quantification data (relative to NGM) obtained after phenolic acids treatment and measured by Nile Red staining. Data correspond to the mean ± SEM. *, **, *** show the level of statistical significance of the differences, p < 0.05, p < 0.01, and p < 0.001, respectively.

Treatment	Mean Fat Content	Integrated Density	Volume	Sample Size (n)
NGM	100.0 ± 0.9	100.0 ± 1.6	100.0 ± 1.4	353
Orlistat	75.3 ± 1.1 ***	62.3 ± 1.8 ***	72.0 ± 2.2 ***	169
p-Coumaric acid
10 µM	97.8 ± 0.9	103.0 ± 2.0	108.7 ± 2.3 **	124
100 µM	97.0 ± 0.9	97.0 ± 1.7	99.7 ± 1.8	180
500 µM	91.9 ± 0.9 ***	94.6 ± 1.8 **	103.4 ± 2.2	92
Ellagic acid
10 µM	97.7 ± 1.2 *	102.0 ± 2.0	108.8 ± 2.5 **	133
100 µM	93.6 ± 1.0 **	94.6 ± 1.9	100.5 ± 2.2	174
500 µM	96.8 ± 1.1	96.3 ± 1.9	98.8 ± 2.1	103
Ferulic acid
10 µM	94.3 ± 0.9 ***	95.0 ± 2.0	101.8 ± 2.2	182
100 µM	92.1 ± 1.0 ***	88.7 ± 2.1 ***	95.3 ± 2.3	190
500 µM	91.3 ± 0.9 ***	91.4 ± 1.7 **	100.3 ± 1.7	119
Gallic acid
10 µM	94.2 ± 0.9 ***	90.8 ± 1.2 ***	93.5 ± 0.9 ***	142
100 µM	96.0 ± 1.4 **	94.9 ± 2.0 **	96.0 ± 1.6 *	136
500 µM	96.5 ± 1.1 **	92.9 ± 1.6 ***	94.2 ± 1.2 ***	120
Vanillic acid
10 µM	94.8 ± 1.1 ***	92.9 ± 1.9 ***	97.4 ± 1.6	126
100 µM	89.2 ± 1.1 ***	86.3 ± 1.7 ***	94.5 ± 1.4 *	187
500 µM	86.6 ± 0.8 ***	80.6 ± 1.4 ***	89.3 ± 1.3 ***	134