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. 2020 Oct 27;9(11):738. doi: 10.3390/antibiotics9110738

Table 2.

Performance of algorithm after application to 1209 clinical P. aeruginosa isolates from a US surveillance study.

Algorithm-Derived Screening Criteria Number Meeting Criteria Carbapenemase Producers Detected Carbapenemase Producers Missed by Criteria
IPM + MEM- Resistant
AND
FEP + CAZ + TZP- Non-Susceptible
116 7/116 0
IPM + MEM- Resistant
AND
FEP + CAZ + TZP- Non-Susceptible + CZA- Resistant
43 7/43 0
IPM + MEM- Resistant
AND
FEP + CAZ + TZP- Non-Susceptible + C/T- Resistant
21 6/21 1 *
IPM + MEM- Resistant
AND
FEP + CAZ + TZP- Non-Susceptible + C/T- Resistant + CZA-Resistant
19 6/19 1 *

IPM = imipenem; MEM = meropenem; FEP = cefepime; CAZ = ceftazidime; TZP = piperacillin/tazobactam; CZA = ceftazidime/avibactam; C/T = ceftolozane/tazobactam. * Genotype: blaOXA-2, blaOXA-50, and PAO.