Table 2.

FE (n = 16) and non-FE (n = 16) group differences in functional connectivity with the (A) left hippocampus, (B) right hippocampus, (C) left insula, (D) right insula, and (E) medial frontal cortex seed regions, after adjusting for age, education, sex, and scores on the Montreal Cognitive Assessment (MoCA).

Seed ROI	Cluster	Regions	MNI coordinates			Cluster size	t-value1
			x	y	z
(a) Left hippocampus	1	Right postcentral gyrus	66	−18	14	215	−4.18
		Right central opercular cortex
		Right planum temporale
(b) Right hippocampus	1	Left temporal pole	−22	0	−48	340	−4.98
		Left temporal fusiform cortex
		Left parahippocampal gyrus
	2	Right temporal fusiform cortex	32	−4	−46	292	−4.78
		Right parahippocampal gyrus
		Right inferior temporal gyrus
	3	Right cerebellum crus	16	−86	−24	213	5.85
		Bilateral lingual gyri
		Right occipital fusiform gyrus
(c) Left insula	1	Anterior cingulate gyrus	6	40	20	224	5.53
		Bilateral paracingulate gyri
	2	Right frontal orbital cortex	38	32	−18	195	5.56
		Right frontal pole
	3	Posterior cingulate gyrus	−4	−26	40	135	5.20
		Anterior cingulate gyrus
(d) Right insula	1	Anterior cingulate gyrus	6	8	36	1218	5.42
		Bilateral paracingulate gyri
	2	Left middle temporal gyrus	−70	−22	−10	269	4.82
		Left superior temporal gyrus
		Left temporal pole
	3	Left dorsolateral prefrontal cortex	−40	46	26	153	4.43
	4	Posterior cingulate gyrus	−4	−22	38	106	5.22
		Anterior cingulate gyrus
(e) Medial frontal cortex	1	Right middle temporal gyrus	58	−4	−8	841	−5.17
		Right superior temporal gyrus
	2	Right temporal pole	40	26	−24	182	−4.98
		Right orbitofrontal cortex
	3	Right postcentral gyrus	44	−6	14	136	4.12
		Right precentral gyrus
		Right central opercular cortex

Note: MNI, Montreal Neurological Institute; ¹Negative t-values reflect regions of greater functional connectivity in the FE group than the non-FE group.