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. 2020 Nov 13;7:542485. doi: 10.3389/fcvm.2020.542485

Figure 4.

Figure 4

The depletion of MAGI1 increases LATS1/2 expression, but the depletion of LATS1/2 shows no effect on MAGI1 expression. (A–C) Levels of MAGI1 and LATS1/2 mRNA expression were quantified in HAECs treated with siMAGI1 with or without siLATS1 and siLATS2, or siCTRL (mean ± SEM, n = 4). (D) Wes analysis of MAGI1 and LATS1/2 protein expression levels in cell lysates collected from HAECs treated with siMAGI1 (100 nM, 48 h), actin serves as a loading control. (E) Quantification of MAGI1 and LATS1/2 expression shown in (D) (mean ± SEM, n = 3). Statistical differences between two independent groups (E,F) were assessed using the Student t-test (two-tailed), and one-way analysis of variance followed by Bonferroni post-hoc testing for multiple group. ***P < 0.001, **P < 0.01, and *P < 0.05.