Figure 2.

Comparison of bactericidal activity of clinically relevant antibiotics against planktonic MBC (blue) and biofilm MBBC (red) of the tested antibiotics against S. epidermidis. Serial dilution and CFU counts were used to compare MBC and MBBC. A Mann–Whitney significance test was used (**** p < 0.0001). Nearly all antibiotics demonstrated significant results, with a p-value of less than 0.0001; however, clindamycin and TMP/sulfa were equally ineffective at eradication of either planktonic or biofilm cultures.