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Strategies before changing ustekinumab.
| Secondary Failure | Arthritis Inefficacy | Patients Intensified | |
|---|---|---|---|
| Methotrexate added (n) (dose) | 3 (15 mg/week) | 3 (15 mg/week) | 1 (15 mg/week) |
| Period between treatments shortened (n) (dose) | 2 (90 mg/8 weeks) 2 (90 mg/10 weeks) |
2 (90 mg/8 weeks) | |
| Dose increased from 45 mg to 90 mg | 1 | 5 | 8 |
