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. 2020 Oct 26;12(11):3126. doi: 10.3390/cancers12113126

Table 1.

Key genetic attributes of patient derived xenographs (PDX) cell lines.

Method Mayo Sarkaria qMS-PCR MD Anderson CLIA qMS-PCR Sanger Sequencing
GBM MGMT METHYLATION MGMT METHYLATION TERT IDH1 IDH2
6 U Indeterminate C228T wt wt
12 M M C250T wt wt
43 U M C228T wt wt

Cell lines used in experiments are all IDH1/2 wildtype. They have two distinct TERT mutations. U = unmethylated, M = methylated.