Table 2.
Immunohistochemical analysis of markers of tumor infiltrating lymphocytes from Id1+/+/DPBS (pLKO-sc LLC), Id1+/+/anti-PD1 (pLKO-sc LLC), Id1-/-/DPBS (Id1sh LLC), and Id1-/-/anti-PD1 (Id1sh LLC) tumors.
| IHC Marker | C57 pLKO-sc PBS | C57 pLKO-sc anti-PD1 | IDKO Id1sh PBS | IDKO Id1sh anti-PD1 | ||||
|---|---|---|---|---|---|---|---|---|
| Median | Interquartile Range | Median | Interquartile Range | Median | Interquartile Range | Median | Interquartile Range | |
| CD3 | 0.158 | 0.089–0.388 | 0.368 | 0.147–0.840 | 0.413 | 0.205–0.711 | 1.136 | 0.626–2.267 |
| CD8 | 0.655 | 0.283–0.949 | 0.403 | 0.320–0.674 | 1.638 | 1.202–1.870 | 2.072 | 1.321–4.045 |
| CD4 | 0.680 | 0.448–1.128 | 0.788 | 0.588–1.783 | 0.887 | 0.539–1.297 | 2.490 | 1.580–4.810 |
| FOXP3 | 0.35 | 0.2–0.615 | 0.280 | 0.230–0.385 | 0.175 | 0.113–0.248 | 0.270 | 0.155–0.385 |