Table 9.

Stability studies for AZM-S-F1_(H) formulation under the three different storage conditions. Mean ± SD, n = 3.

Parameters	Time (Months)
	0	0.5	1	2	3
Refrigerator (4 ± 3 °C)
Physical stability
DS (nm)	155.93 ± 1.39	155.13 ± 1.35	156.27 ± 1.19	157.33 ± 0.59	159.2 ± 0.78
Đ	0.64 ± 0.04	0.65 ± 0.015	0.64 ± 0.015	0.66 ± 0.021	0.66 ± 0.01
ZP (mV)	−19.28 ± 0.45	−19.23 ± 0.32	−19.27 ± 0.45	−18.97 ± 0.75	−18.49 ± 0.6
Chemical stability
DC (%)	98.599 ± 0.32	98.52 ± 0.38	98.41 ± 0.57	98.37 ± 0.2	98.09 ± 0.5
Room condition (25 ± 2 °C/60 ± 5% RH)
Physical stability
DS (nm)	155.93 ± 1.39	155.8 ± 1.67	155.6 ± 1.25	158.3 ± 1.25	161.55 ± 1.1
Đ	0.64 ± 0.04	0.627 ± 0.025	0.65 ± 0.02	0.647 ± 0.03	0.68 ± 0.006
ZP (mV)	−19.28 ± 0.45	−19.15 ± 0.53	−18.97 ± 0.31	−18.77 ± 0.31	−16.27 ± 0.45
Chemical stability
DC (%)	98.599 ± 0.32	98.42 ± 0.12	98.34 ± 0.36	98.06 ± 0.33	97.92 ± 0.43
Humidity chamber (40 ± 2 °C/75 ± 5% RH)
Physical stability
DS (nm)	155.93 ± 1.39	156.4 ± 0.6	158 ± 1	162.37 ± 1.1	164.1 ± 1.02
Đ	0.64 ± 0.04	0.65 ± 0.01	0.653 ± 0.015	0.657 ± 0.015	0.603 ± 0.006
ZP (mV)	−19.28 ± 0.45	−19.03 ± 0.4	−18.9 ± 0.3	−18.63 ± 0.42	−15.3 ± 0.56
Chemical stability
DC (%)	98.599 ± 0.32	98.44 ± 0.28	98.014 ± 0.4	97.86 ± 0.37	97.48 ± 0.58

(DS, Droplet size; Đ, Dispersity; ZP, Zeta potential; DC%, Drug content percentage; RH, Relative humidity).