Table 4.
Effects of Graviola and MSG extract on liver oxidative status of different rat groups.
| Parameters | Control | Graviola | MSG | Graviola + MSG | MSG + Graviola |
|---|---|---|---|---|---|
| MDA (nmol/g) | 685.8 ± 36.30 c | 678.2 ± 36.31 c | 1216 ± 18.01 a | 800.4 ± 18.88 b | 815.8 ± 18.80 b |
| NO (μ mol/g) | 18.23 ± 0.52 c | 18.11 ± 0.50 c | 35.48 ± 0.54 a | 25.00 ± 0.50 b | 26.10 ± 0.55 b |
| H2O2 (mM/g) | 1.32 ± 0.10 c | 1.28 ± 0.12 c | 4.83 ± 0.15 a | 3.30c ± 0.10 b | 3.37 ± 0.11 b |
| SOD (U/g) | 92.09 ± 2.77 a | 95.31 ± 2.40 a | 59.28 ± 2.56 c | 79.48 ± 2.66 b | 75.84 ± 2.54 b |
| CAT (U/g) | 189.5 ± 4.40 a | 192.0 ± 2.89 a | 128.5 ± 4.06 d | 170.6 ± 4.66 c | 165.4 ± 4.54 b |
| GST (U/g) | 5.40 ± 0.57 a | 5.87 ± 0.57 a | 1.25 ± 0.22 c | 3.24 ± 0.40 b | 3.06 ± 0.24 b |
| GSH (mmol/g) | 5.50 ± 0.24 a | 5.54 ± 0.29 a | 2.86 ± 0.17 c | 4.20 ± 0.16 b | 4.00 ± 0.15 b |
Data presented as means ± SEM for six rats in each group and % of change. The significant change at p ≤ 0.05 (N = 6). Different superscript letters (a, b, c and d) indicate significant differences in the same column. Malondialdehyde (MDA), nitric oxide (NO), glutathione (GSH), glutathione S transferase (GST), superoxide dismutase (SOD), and catalase (CAT).