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. 2020 Oct 29;12(11):1035. doi: 10.3390/pharmaceutics12111035

Table 1.

EE%, LC%, and LC in mg mg (Drug)/mg (MSN-NH2) of DEX MSN-NH2 and 5-FU MSN-NH2 using different drug: MSN-NH2 ratios.

Ratio
Drug:MSN-NH2
(Drug:MSN-NH2)
(mg in 25 mL)
EE% LC% LC
mg (Drug)/mg (MSN-NH2)
DEX
1:5 5:25 47.4 ± 3.15 8.66 ± 0.63 0.087 ± 0.006 mg/1 mg
1:1 25:25 18.89 ± 0.89 15.89 ± 0.88 0.159 ± 0.009 mg/1 mg
5:1 125:25 15.92 ± 0.79 44.72 ± 4.21 0.447 ± 0.042 mg/1 mg
5-FU
1:1 25:25 18.01 ± 3.72 15.26 ± 3.13 0.153 ± 0.031 mg/1 mg.
5:1 125:25 3.6 ± 1.4 12.6 ± 5.50 0.126 ± 0.055 mg/1 mg.