Table 1.
Patient characteristics according to whether baseline PAD was present or not.
| Characteristic | Overall | PAD at Baseline | p Value | |
|---|---|---|---|---|
| (n = 234) | No (n = 200) |
Yes (n = 34) |
||
| Age (years) | 63 ± 13 | 62 ± 13 | 69 ± 11 | 0.007 |
| Male sex, n (%) | 128 (54.7%) | 109 (54.5%) | 19 (55.9%) | 0.881 |
| Current smoker, n (%) | 27 (11.5%) | 22 (11.0%) | 5 (14.7%) | 0.532 |
| DM, n (%) | 103 (44.0%) | 74 (37.0%) | 29 (85.3%) | <0.001 |
| CVD, n (%) | 76 (32.5%) | 58 (29.0%) | 18 (52.9%) | 0.006 |
| CAD, n (%) | 64 (27.4%) | 49 (24.5%) | 15 (44.1%) | 0.018 |
| Stroke, n (%) | 18 (7.7%) | 13 (6.5%) | 5 (14.7%) | 0.097 |
| Dialysis vintage (years) | 2.4 (1.4–3.7) | 2.4 (1.4–3.7) | 2.6 (2.1–4.0) | 0.109 |
| BMI (kg/m2) | 23.6 ± 3.8 | 23.6 ± 3.7 | 23.7 ± 4.1 | 0.849 |
| ABI | 1.06 ± 0.20 | 1.10 ± 0.16 | 0.81 ± 0.27 | <0.001 |
| Systolic BP (mmHg) | 138 ± 20 | 138 ± 20 | 136 ± 19 | 0.533 |
| RAASi, n (%) | 75 (32.1%) | 64 (32.0%) | 11 (32.4%) | 0.967 |
| Anti-platelet, n (%) | 52 (22.2%) | 34 (17.0%) | 18 (52.9%) | <0.001 |
| Statin, n (%) | 35 (15.0%) | 22 (11.0%) | 13 (38.2%) | <0.001 |
| Kt/V | 1.8 ± 0.3 | 1.8 ± 0.3 | 1.9 ± 0.3 | 0.318 |
| URR (%) | 78.0 ± 5.5 | 77.8 ± 5.7 | 78.6 ± 4.9 | 0.446 |
| nPCR (g/kg/day) | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.0 ± 0.2 | 0.103 |
| Hemoglobin (g/dL) | 10.5 ± 1.2 | 10.5 ± 1.2 | 10.4 ± 1.3 | 0.893 |
| Albumin (g/dL) | 3.9 ± 0.4 | 3.9 ± 0.4 | 3.8 ± 0.3 | 0.170 |
| TC (mg/dL) | 158 (136–184) | 159 (138–184) | 152 (125–192) | 0.446 |
| HDL-C (mg/dL) | 39 (31–49) | 40 (31–50) | 35 (27–46) | 0.149 |
| LDL-C (mg/dL) | 89 (73–107) | 91 (73–107) | 81 (69–101) | 0.142 |
| Triglycerides (mg/dL) | 123 (85–193) | 126 (86–191) | 112 (79–240) | 0.942 |
| TC:HDL-C | 4.0 (3.0–5.3) | 3.9 (3.0–5.4) | 4.5 (2.9–5.3) | 0.626 |
| Fasting glucose (mg/dL) | 98 (87–129) | 96 (87–126) | 110 (89–150) | 0.112 |
| Calcium (mg/dL) | 9.3 (8.8–9.8) | 9.4 (8.9–9.9) | 9.1 (8.8–9.6) | 0.140 |
| Phosphate (mg/dL) | 4.6 (3.7–5.7) | 4.6 (3.8–5.7) | 4.2 (3.1–5.7) | 0.236 |
| Intact PTH (pg/mL) | 265 (126–431) | 264 (117–429) | 269 (156–436) | 0.954 |
| CRP (mg/L) | 0.27 (0.12–0.63) | 0.27 (0.11–0.59) | 0.32 (0.21–0.79) | 0.153 |
| Indoxyl sulfate (μg/mL) | 45.9 (29.9–62.6) | 46.0 (29.7–62.9) | 44.4 (30.4–62.2) | 0.992 |
Abbreviations: ABI, ankle-brachial index; BMI, body mass index; BP, blood pressure; CAD, coronary artery disease; CRP, C-reactive protein; CVD, cardiovascular disease; DM, diabetes mellitus; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; nPCR, normalized protein catabolic rate; PAD, peripheral artery disease; PTH, parathyroid hormone; RAASi, renin-angiotensin-aldosterone system inhibitors; TC, total cholesterol; URR, urea reduction rate.