Table 2.
Patient characteristics according to whether incident PAD was present or not.
| Characteristic | Patients without Incident PAD (n = 163) |
Patients with Incident PAD (n = 37) |
p Value |
|---|---|---|---|
| Age (years) | 61 ± 14 | 66 ± 10 | 0.045 |
| Male sex, n (%) | 86 (52.8%) | 23 (62.2%) | 0.300 |
| Current smoker, n (%) | 19 (11.7%) | 3 (8.1%) | 0.533 |
| DM, n (%) | 49 (30.1%) | 25 (67.6%) | <0.001 |
| CVD, n (%) | 40 (24.5%) | 18 (48.6%) | 0.004 |
| CAD, n (%) | 33 (20.2%) | 16 (43.2%) | 0.003 |
| Stroke, n (%) | 10 (6.1%) | 3 (8.1%) | 0.660 |
| Dialysis vintage (years) | 2.4 (1.3–3.6) | 2.4 (1.4–5.2) | 0.876 |
| BMI (kg/m2) | 23.4 ± 3.8 | 24.2 ± 3.5 | 0.226 |
| Systolic BP (mmHg) | 138 ± 19 | 140 ± 22 | 0.650 |
| RAASi, n (%) | 50 (30.7%) | 14 (37.8%) | 0.399 |
| Anti-platelet, n (%) | 24 (14.7%) | 10 (27.0%) | 0.072 |
| Statin, n (%) | 15 (9.2%) | 7 (18.9%) | 0.088 |
| Kt/V | 1.8 ± 0.3 | 1.8 ± 0.3 | 0.612 |
| URR (%) | 77.9 ± 5.6 | 77.0 ± 6.0 | 0.393 |
| nPCR (g/kg/day) | 1.1 ± 0.3 | 1.1 ± 0.3 | 0.938 |
| Hemoglobin (g/dL) | 10.5 ± 1.3 | 10.4 ± 1.0 | 0.796 |
| Albumin (g/dL) | 3.9 ± 0.4 | 3.9 ± 0.3 | 0.731 |
| TC (mg/dL) | 158 (136–184) | 162 (140–186) | 0.763 |
| HDL-C (mg/dL) | 41 (32–51) | 37 (29–44) | 0.089 |
| LDL-C (mg/dL) | 90 (73–106) | 95 (74–115) | 0.607 |
| Triglycerides (mg/dL) | 126 (82–190) | 121 (87–237) | 0.352 |
| TC:HDL-C | 3.8 (2.9–5.4) | 4.3 (3.3–5.4) | 0.178 |
| Fasting glucose (mg/dL) | 95 (87–122) | 110 (89–147) | 0.193 |
| Calcium (mg/dL) | 9.4 (8.9–9.9) | 9.2 (8.8–9.9) | 0.486 |
| Phosphate (mg/dL) | 4.6 (3.8–5.7) | 4.5 (3.8–5.8) | 0.927 |
| Intact PTH (pg/mL) | 267 (116–422) | 219 (116–450) | 0.882 |
| CRP (mg/L) | 0.25 (0.12–0.58) | 0.27 (0.10–0.61) | 0.727 |
| Indoxyl sulfate (μg/mL) | 45.2 (28.5–61.7) | 56.2 (40.9–69.0) | 0.033 |
Abbreviations: BMI, body mass index; BP, blood pressure; CAD, coronary artery disease; CRP, C-reactive protein; CVD, cardiovascular disease; DM, diabetes mellitus; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; nPCR, normalized protein catabolic rate; PAD, peripheral artery disease; PTH, parathyroid hormone; RAASi, renin-angiotensin-aldosterone system inhibitors; TC, total cholesterol; URR, urea reduction rate.