Table 1.
Risk factors associated with COVID-19 mortality on bivariate analysis
| Variable | Cured | No cured | p value |
|---|---|---|---|
| Sex—male | 28.9 (22) | 66.7 (16) | < 0.001 |
| Age* | 86.5 (7.6) | 86.1 (8.9) | 0.888 |
| Flu vaccine | 78.9 (60) | 66.7 (16) | 0.219 |
| Temperature > 37.5º | 52.6 (40) | 79.2 (19) | 0.021 |
| Respiratory symptoms | 50.0 (38) | 79.2 (19) | 0.012 |
| Ha side effects | 2.8 (2) | 13.0 (3) | 0.090 |
| Treatment H + Aa | 81.6 (62) | 33.3 (8) | < 0.001 |
| Hb | 7.9 (6) | 12.5 (3) | |
| No treatmentc | 10.5 (8) | 54.2 (13) | |
| Treatment started in the first 24 h | 39.5 (30) | 37.5 (9) | 0.863 |
| Serum therapy | 43.4 (33) | 79.2 (19) | 0.002 |
| Oxygen therapy | 50.0 (38) | 95.8 (23) | < 0.001 |
| Severe cognitive decline (GDS 5–7) | 67.1 (51) | 91.7 (22) | 0.018 |
| Charlson* | 5.7 (2.0) | 6.0 (2.5) | 0.183 |
| Barthel index* | 43.3 (39.9) | 18.8 (23.6) | 0.021 |
| Severe/totally dependency (Barthel ≤ 60) | 65.8 (50) | 91.7 (22) | 0.014 |
| Ferritin (log)* | 6.0 (1.1) | 6.6 (1.3) | 0.106 |
| LDH (log)* | 6.2 (0.3) | 6.4 (0.4) | 0.033 |
| Anemia | 43.2 (32) | 26.7 (4) | 0.233 |
| Lymphocytopenia | 37.8 (28) | 66.7 (10) | 0.040 |
| Thrombocytopenia | 25.7 (19) | 33.3 (5) | 0.542 |
| D DIMER (log)* | 0.31 (0.86) | 1.04 (0.97) | 0.015 |
| CRP (log)* | 3.2 (1.6) | 4.1 (1.4) | 0.063 |
| Troponin (log)* | 3.5 (0.7) | 4.4 (1.1) | 0.092 |
% (N) for categorical variables and means (SD) for quantitative (*)
H + Aa hydroxychloroquine and azithromycin, Hb hydroxychloroquine
No treatment c includes Others: Beta-lactam or Quinolone antibiotics