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Celecoxib release profiles of A1C, G1C, and N-GA1C in liver homogenate and plasma. (a,b) Percentages of celecoxib released from the prodrugs after incubation with 20% suspension of liver homogenate (a) or blood plasma (b) in IPB. Data are presented as mean ± s.e.m. from a representative experiment (n = 5) from 2 independent experiments. **** p < 0.0001, analyzed by two-way ANOVA with Tukey’s HSD multiple comparison post hoc test.
