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. 2020 Oct 28;10(11):1488. doi: 10.3390/biom10111488

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of pre-treatment with linalool (50 and 100 mg/kg) for 14 days on the inflammatory mediators (a) TNF-α, (b) NF-κB, (c) IL-1β, and (d) IL-6 in cisplatin-induced acute kidney injury. All values are expressed as mean ± SD. # indicates statistically significant from normal control group, * indicates statistically significant from cisplatin-only group, and @ indicates statistically significant from cisplatin + linalool 50 mg/kg group (p < 0.05) using one-way ANOVA followed by Tukey’s post-hoc test.