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. 2020 Nov 3;12(11):1051. doi: 10.3390/pharmaceutics12111051

Table 3.

Fixed-bed bioreactors optimized for high-scale LV production.

Device iCELLis Nano Scale-X Hydro iCELLis 500+ Scale-X Nitro
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Surface 2.67 m2 2.4 m2 333 m2 200–600 m2
Total viral particles (vp) >1013 >1013 9.27 × 1014 Not optimized yet
Vp/cm2 >109 >109 9.27 × 108 Not optimized yet
Total transducing units (TU) 1.3 × 1010 2.4 × 1010 1.12 × 1012 Not optimized yet
TU/cm2 4.7 × 105 9.8 × 105 2.3 × 105 Not optimized yet
Yield Not concentrated Not concentrated 1.97 × 109 TU/mL Not optimized yet