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. 2020 Nov 4;8(11):1722. doi: 10.3390/microorganisms8111722

Figure 5.

Figure 5

Binding total IgG antibodies to scaffolded gp70V1V2 protein of CRF01_AE and subtype C and IgG1 and IgG3 antibodies to scaffolded gp70V1V2 protein of CRF01_AE in plasma samples from a subset of vaccinees (n = 57). The Mann–Whitney test was used to compare the magnitude of V1V2 specific antibody responses between the two vaccination groups. There was no significant difference between the two vaccination groups in the magnitude of total IgG responses to CRF01_AE (A) or subtype C (B) V1V2 protein. No significant difference in the magnitude of anti-V1V2 IgG1 responses against CRF01_AE was seen between the two groups, p = 0.1776 (C). IgG3 antibodies binding to CRF01_AE V1V2 protein were significantly more frequent in recipients of HIV-MVA boost alone, p = 0.0132 (D). The dotted line indicates the first dilution used. Results are reported as reciprocal values of end-point titers.