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. 2020 Oct 24;8(11):450. doi: 10.3390/biomedicines8110450

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Characterization of WT SC-derived EV cargo in terms of miRNA content. Upset plot that shows the instances where more than 2 miRNAs target more than 5 genes. The plot is made using the R package “UpSetR”. The blue bars on the left side of the plot show the number of targets predicted for each miRNA. The right-side bar plot show the number of genes targeted by only a single miRNA (single black dot in the lower right panel) or multiple miRNAs (multiple linked dots in the lower right panel).