Table 1.
Histopathological changes in the tongue tissues of mice in each group.
| Group (n) | No. (%) of Biopsies | ||||||
|---|---|---|---|---|---|---|---|
| Normal | Squamous Hyperplasia | Mild Dysplasia | Moderate Dysplasia | Severe Dysplasia | Squamous Cell Carcinoma | Survival * | |
| C0F− (5) | 5 (100%) | 0 | 0 | 0 | 0 | 0 | 5 (100%) |
| C0F+ (5) | 0 | 0 | 0 | 3 (60%) | 2 (40%) | 0 | 5 (100%) |
| C8F− (10) | 0 | 0 | 3 (30%) | 1 (10%) | 2 (20%) | 4 (40%) | 8 (80%) |
| C8F+ (10) | 0 | 0 | 0 | 2 (20%) | 5 (50%) | 3 (30%) | 8 (80%) |
| C10F− (10) | 0 | 0 | 0 | 3 (30%) | 4 (40%) | 3 (30%) | 9 (90%) |
| C10F+ (10) | 0 | 0 | 0 | 0 | 1 (10%) | 9 (90%) | 10 (100%) |
“*”: survival before sacrifice.