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. 2020 Nov 2;12(11):3230. doi: 10.3390/cancers12113230

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Proportions of myeloid and T cell subsets in glioma samples. (A–C) Percentage of neutrophils (A), myeloid-derived suppressor cells (MDSCs) (B) and macrophages (C) on total tumor suspensions from IDHmut (IDHmut LGG and GBM) (n = 6), GBMwt_lo (n = 5), and GBMwt_hi (n = 6) gliomas. (D–E) Percentage of CD206⁺ myeloid cells (D) and myeloid to lymphoid ratio (E) on total tumor suspensions from IDHmut (n = 4), GBMwt_lo (n = 6), and GBMwt_hi (n = 10) gliomas. (F–I) Percentage of T cells (F), CD4⁺ T cells (G) and CD8⁺ T cells (H) and ratio of CD4⁺ to CD8⁺ T cells (I) on total tumor suspensions from IDHmut (n = 4), GBMwt_lo (n = 6), and GBMwt_hi (n = 10) gliomas. (J–K) Percentage of PD1⁺ T cells (J) and T regs (K) within the CD45⁺ tumor subset of IDHmut (n = 5), GBMwt_lo (n = 6), and GBMwt_hi (n = 7) gliomas. * p < 0.05, ** p < 0.01, *** p < 0.001, ns: not significant.