ATRX	α-thalassemia/mental retardation syndrome X-linked
BBB	blood–brain barrier
BV	blood vessels
CGP	chemical and genetic perturbations
CL	classical
FFPE	formalin-fixed paraffin-embedded
CP	canonical pathways
GSEA	gene set enrichment analysis
GBM	glioblastoma
GBMwt_hi	a subgroup of IDH wild-type tumors with a high content of CD45+ cells (more than 15% of the cellular suspension)
GBMwt_lo	a subgroup of IDH wild-type tumors with a low content of CD45+ cells (less than 15% of the cellular suspension)
IBA1	ionized calcium binding adaptor molecule 1
ICI	immune checkpoint inhibitors
IDH1/2	isocitrate dehydrogenase 1/2
IHC	immunohistochemistry
LGG	lower-grade glioma
MDSC	Myeloid-derived suppressor cells
MES	mesenchymal
MGMT	O6-methylguanine-DNA-methyltransferase
mut	mutant
ns	not significant
PCR	polymerase chain reaction
PD-1	programmed cell death 1
PD-L1	programmed death ligand 1
PN	proneural
RT	room temperature
SEM	standard error of the mean
TCGA	the cancer genome atlas
TME	tumor microenvironment
Tregs	regulatory T cells
VEGF	vascular endothelial growth factor
wt	wild-type