Table 2.
Effect of boldenone (5 mg/kg bwt/once a week, eight weeks) and/or vitamin C (120 mg/kg b.wt/daily, eight weeks) treatment on hormonal variables and testicular enzymes of adult male Wister rats.
| Groups | Control | Vehicle Control | Vit-C | BOL | BOL+Vit-C | p-Value |
|---|---|---|---|---|---|---|
| Serum TES (ng/mL) | 2.87 b ± 0.31 | 3.65 b ± 0.23 | 3.88 b ± 0.75 | 7.19 a ± 0.08 | 6.12 a ± 0.79 | <0.001 |
| Testicular TES (ng/g tissue) | 406.40a ± 9.86 | 400.00a ± 13.76 | 400.00 a ± 14.71 | 147.20 b ± 5.99 | 171.20b ± 8.16 | <0.001 |
| LH (mIU/mL) | 3.43 a ± 0.08 | 3.51 a ± 0.06 | 3.53 a ± 0.06 | 2.28 b ± 0.32 | 2.67 b ± 0.15 | <0.001 |
| FSH (ng/mL) | 8.31 a ± 0.39 | 8.35 a ± 0.23 | 8.45 a ± 0.29 | 4.54 b ± 0.50 | 5.63 b ± 0.38 | <0.001 |
| E2 (pg/mL) | 59.77 a ± 3.20 | 58.10 a ± 3.34 | 57.67 a ± 3.14 | 28.20 b ± 1.28 | 35.13b ± 1.82 | <0.001 |
| ACP (U/L) | 15.67 c ± 1.65 | 16.67c ± 1.43 | 16.33 c ± 1.25 | 47.33 a ± 2.72 | 25.67 b ± 2.46 | <0.001 |
| SDH (ng/mL) | 1.38 c ± 0.07 | 1.39 c ± 0.19 | 1.38 c ± 0.10 | 5.00 a ± 0.14 | 2.36 b ± 0.26 | <0.001 |
BOL: boldenone; Vit-C: vitamin C; TES: testosterone; LH: luteinizing hormone; FSH: follicle-stimulating hormone; E2: estradiol; ACP: acid phosphatase; SDH: sorbitol dehydrogenase. A one-way analysis of variance (ANOVA) followed by Duncan’s Multiple Range Test was used for statistical analysis. Means within the same row carrying different superscripts (a–d) are significantly different. The values shown are the means ± SE. n = 8.