Table 3.

Lesion scoring in the testicular tissues of rats in response to boldenone (5 mg/kg bwt/once a week, 8 weeks) and/or vitamin C (120 mg/kg b.wt/daily, 8 weeks) treatment.

Lesion	Control	Vehicle Control	Vit-C	BOL	Vit-C+BOL	p-Value
ST/10X	15.40 b ± 0.69	15.90 b ± 0.67	15.50 b ± 0.72	24.60 a ± 0.70	23.00 a ± 0.61	<0.001
Diameter of ST	275.09 a ± 6.22	275.58 a ± 6.07	279.05 a ± 5.80	175.23 b ± 11.33	184.41 b ± 10.81	<0.001
Height of germinal epithelium/ST	83.18 a ± 1.68	83.54 a ± 1.58	83.81 a ± 2.09	44.04 b ± 3.08	46.26 b ± 2.26	<0.001
ST with vacuolated germinal epithelium	0.00 c ± 0.00	0.00 c ± 0.00	0.00 c ± 0.00	5.66 a ± 0.73	4.05 b± 0.23	<0.001
ST with detached germinal epithelium	0.12 c ± 0.12	0.13 c ± 0.13	0.13 c ± 0.13	18.10 a ± 1.22	14.54 b ± 1.96	<0.001
STs with depleted germ cells	0.00 c ± 0.00	0.00 c ± 0.00	0.00 c ± 0.00	64.89 a ± 3.73	57.86 b ± 3.60	<0.001
ST with necrotic germinal epithelium	0.00 c ± 0.00	0.00 c ± 0.00	0.00 c ± 0.00	58.65 a ± 2.39	50.07 b ± 1.67	<0.001
STs with complete loss of germ cells	0.00 c ± 0.00	0.00 c ± 0.00	0.00 c ± 0.00	2.04 a ± 0.35	1.22 b ± 0.18	<0.001
STs with redundant basement membranes	0.00 b ± 0.00	0.00 b ± 0.00	0.00 b ± 0.00	0.99 a ± 0.30	0.45 b ± 0.25	<0.001
Spermatid retention	0.00 c ± 0.00	0.00 c ± 0.00	0.00 c ± 0.00	0.65 a ± 0.02	0.32 b ± 0.01	<0.001
Interstitial leukocytic infiltration	0.00 c ± 0.00	0.00 c ± 0.00	0.00 c ± 0.00	4.10 a ± 0.80	2.05 b ± 0.40	<0.001
Interstitial edema	0.00 c ± 0.00	0.00 c ± 0.00	0.00 c ± 0.00	8.00 a ± 0.73	4.00 b ± 0.37	<0.001
Interstitial congestion	0.00 b ± 0.00	0.00 b ± 0.00	0.00 b ± 0.00	10.00 a ± 3.33	4.00 b ± 2.67	0.001

BOL: boldenone and Vit-C: vitamin C.Values are mean ± SE for n = 5 samples/group. Means within the same row (in each parameter) carrying different superscripts (a, b, and c) are significantly different at p < 0.05 groups. Data are expressed as the mean ± SE (n = 8 replicates). Columns carrying different superscripts (^a–c) are significantly different (one-way ANOVA).