Skip to main content
. 2020 Oct 29;18(11):541. doi: 10.3390/md18110541

Figure 5.

Figure 5

Immunomodulatory effects of Penicillium purpurogenum ethyl acetate extract. (a–d) The results are expressed as the mean ± standard deviation of the total lymph node cell count; bone marrow and splenocytes obtained from the group without tumors treated with saline solution (Sham) from the groups with solid Ehrlich tumors treated intraperitoneally with extracts at doses of 4, 20, and 100 mg/kg, respectively (EAE4, EAE20, and EAE100); positive and negative control-administered cyclophosphamide (CLT+) and saline solution (CTL−), respectively. Blood serum was used to quantify the tumor necrosis factor (TNF-α). The data were submitted to statistical analyses via Kruskal–Wallis and Dunn multiple comparison tests, with a significance of ∆ p < 0.05, ∆∆ p < 0.005, ∆∆∆ p < 0.0005, and ∆∆∆∆ p < 0.0001 in relation to the Sham: ϕ p < 0.05, ϕϕϕϕ p < 0.0001 when compared to EA20 without tumor; #### p < 0.0001 when compared to CLT+, * p < 0.05, ** p < 0.005, *** p < 0.0005, and **** p < 0.0001 when compared to CLT−; and οο p < 0.0001 οοο p < 0.0001 when comparing the extracts with each other.