Effect of the toxicity of the extracellular extract of Penicillium purpurogenum ethyl acetate extract (EAE). The groups without tumor induction were treated with saline (sham), while the groups with induction received the extract at doses of 4, 20, and 100 mg/kg (EAE4, EAE20, and EAE100), as well as saline (CTL−) and cyclophosphamide (CTL+). The graphs show (a) the animals’ body weights in the final treatment. (b) After the treatment of the animals, the animals remained under observation for thirty days. The data represent the mean ± SEM. The difference was statistically analyzed by a Kruskal–Wallis and Dunn’s multiple comparison test, with significance of ∆ p < 0.05, ∆∆ p < 0.005, and ∆∆∆ p < 0.0005 in relation to the Sham, ϕ p < 0.05 ϕϕ p < 0.005, and ϕϕϕ p < 0.0005 when compared to EA20 without a tumor, ο p < 0.05 when compared to CLT+, and οοο p < 0.0005 when compared to CLT−, * p < 0.05, ** p < 0.005, and #### p < 0.0001.