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. 2020 Oct 29;11(11):1277. doi: 10.3390/genes11111277

Figure 7.

Figure 7

CdMWnt11 significantly improves cardiac contractile function and increases angiogenesis in ischemic myocardium. (A): The protein levels of Wnt11 in myocardium following left anterior descending coronary artery (LAD) ligation were evaluated using Western blot and semi-quantitative data. (B): Cardiac function calculated from echocardiography images of rats undergone LAD ligation for 4 weeks. (C): Representative middle heart sections that were stained with Masson’s trichrome. (D,E): Quantitative data of left ventricle wall thickness and fibrosis. (F): Blood flow in the infarcted and border zones. (G): Representative photomicrographs showed vWF-positive cells and the quantitation of vWF-positive capillary density. *, p < 0.05 vs. control (CON); #, p < 0.05 vs. CdMGFP, respectively. In Panel (A): n = 3; In Panels (B,F): CON: n = 6; CdMGFP: n = 6, and CdMWnt11: n = 7. In Panels (C–E,G), CON: n = 6; CdMGFP: n = 7; and CdMWnt11: n = 9.