Table 3.
Independent predictors of hospital mortality according to multivariate logistic regression analysis.
| Variables | Odds Ratio (95% CI) | p Value |
|---|---|---|
| Model 1 | ||
| APACHE II score at ICU admission | 1.22 (1.02–1.46) | 0.03 |
| History of diabetes mellitus | 1.81 (0.20–16.49) | 0.60 |
| NLR | 1.07 (1.02–1.14) | 0.01 |
| Platelet | 1.00 (0.99–1.01) | 0.74 |
| Procalcitonin | 1.99 (0.11–36.42) | 0.64 |
| Model 2 | ||
| NLR level | p for trend | |
| Low (≤16.2) | Reference | 0.005 |
| Medium (16.2–24.0) | 24.11 (1.81, 320.67) | |
| High (≥24.0) | 30.13 (2.62, 347.06) | |
| Model 3 | ||
| APACHE II score at ICU admission | 1.28 (1.07, 1.54) | 0.007 |
| History of diabetes mellitus | 2.13 (0.23–19.49) | 0.50 |
| Neutrophil count | 1.17 (1.00–1.37) | 0.06 |
| PLR | 1.001 (1.00–1.003) | 0.10 |
| Procalcitonin | 0.52 (0.03–9.01) | 0.66 |
| Model 4 | ||
| APACHE II score at ICU admission | 1.19 (0.91–1.55) | 0.20 |
| History of diabetes mellitus | 0.30 (0.01–7.36) | 0.46 |
| NLR | 1.08 (1.00–1.16) | 0.045 |
| Platelet | 1.001 (0.99–1.01) | 0.87 |
| Procalcitonin | 31.08 (0.20–4935.41) | 0.18 |
| Bacterial infection | 76.0 (3.41–1694.15) | 0.006 |
Model 1 chose hospital mortality as the dependent variable and was adjusted for APACHE II score at ICU admission, history of diabetes mellitus, NLR, platelet count, and procalcitonin level. Model 2 chose hospital mortality as the dependent variable and was adjusted for APACHE II score at ICU admission, history of diabetes mellitus, NLR (as a categorical variable), platelet count, and procalcitonin level. Model 3 chose hospital mortality as the dependent variable and was adjusted for APACHE II score at ICU admission, history of diabetes mellitus, neutrophil count, PLR, and procalcitonin level. Model 4 chose hospital mortality as the dependent variable and was adjusted for APACHE II score at ICU admission, history of diabetes mellitus, NLR, platelet count, procalcitonin level, and bacterial infection. As the APACHE II score has repeated items of PaO2/FiO2 ratio and white blood cell count, APACHE II score was added only to the multivariate analysis. APACHE II, Acute Physiology and Chronic Health Evaluation II; CI, confidence interval; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio.