Table 1.

Population, Intervention, Comparison, Outcome, Study design (PICOS) criteria for trial selection cited.

PICOS Item	Inclusion Criteria
Population	Healthy or diseased children, adults and/or older adults
Intervention	Food, extract or pure polyphenols tested alone. No other bioactive compound or drug
Comparison	Control group without polyphenols
Outcome	Any effect on human health and bioavailability
Study design	No restriction on study design