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. 2020 Nov 4;12(11):3264. doi: 10.3390/cancers12113264

Table 3.

Dysregulated circRNAs in thyroid cancer.

circRNA Alteration Mechanism Sample Thyroid Cancer Type Ref.
circ_0008274 ↓ AMPK/mTOR signaling pathway Cell line and tissue PTC [141]
circEIF6 ↓ miR-144-3p → ↑ TGF-α Cell line and tissue PTC & ATC [142]
circFOXM1 ↓ miR-1179 → ↑ HMGB1 Cell line and tissue PTC [143]

PTC: Papillary Thyroid Cancer; ATC: Anaplastic Thyroid Cancer; circFOXM1: Circular Forkhead Box Protein M1; circEIF6: circular Eukaryotic Translation Initiation Factor 6; HMGB1: High Mobility Group Box Protein 1; AMPK: 5′ AMP-activated Protein Kinase; mTOR: Mammalian Target of Rapamycin (mTOR); TGF-α: Transforming Growth Factor Alpha.