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. 2020 Nov 27;20:572. doi: 10.1186/s12935-020-01666-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Circ_0015756 acts as a miR-942-5p sponge. a Three websites (circBank, Starbase 3.0 and circinteractome) were used to predict potential miRNAs that might bind to circ_0015756. b After transfection with si-circ_0015756, the levels of four possible targets (miR-942-5p, miR-145-5p, miR-149-5p and miR-224-5p) were detected. c The putative binding site between circ_0015756 and miR-942-5p was depicted by circinteractome. d The overexpression efficiency of miR-942-5p was detected by qRT-PCR. The binding relationship between circ_0015756 and miR-942-5p was verified by dual-luciferase reporter assay (e, f), RIP assay (g, h) and RNA pull-down assay (i) in OV90 and SKOV3 cells. j The level of miR-942-5p was determined in OV90 and SKOV3 cells transfected with si-NC or si-circ_0015756. k, l The expression of miR-942-5p in OC tissues and cells was tested by qRT-PCR. *P < 0.05