Fig. 6.

CUL4B reverses the effect of miR-942-5p on OC cell progression. a, b The overexpression efficiency of CUL4B was detected by qRT-PCR and Western blot. c–k OV90 and SKOV3 cells were transfected with miR-NC, miR-942-5p, miR-942-5p+ pcDNA or miR-942-5p+ pcDNA-CUL4B. CCK-8, colony formation and Western blot assays were utilized to evaluate cell proliferation capacity (c–e) and proliferation-related protein levels (f, g). Flow cytometry, transwell and Western blot assays were used to assess cell apoptosis (h), migration and invasion (i, j) and metastasis-related protein levels (k). *P < 0.05