Skip to main content
. 2020 Nov 5;12(11):3270. doi: 10.3390/cancers12113270

Table 1.

Twenty-one of the top 100 discordantly expressed genes (positive protein LFC but negative transcript LFC) also found to be present in the published Human Plasma Peptide Atlas consisting of 1929 canonical protein sequences [28]. Shown are overlapping genes with respective LFC, rank and average rank values. Table S3C details discordantly expressed proteins also identified in the human plasma proteome reference set.

Gene Symbol Protein Name LFC Transcript Rank Transcript LFC Protein Rank Protein Average Rank
MBP Myelin basic protein −1.21 3521 2.05 3234 3377.5
PACS1 Phosphofurin acidic cluster sorting protein 1 −0.51 3218 3.34 3534 3376
APP Amyloid-beta precursor protein −0.77 3395 2.26 3318 3356.5
DSP Desmoplakin −1.43 3544 1.48 2938 3241
FCGBP IgGFc-binding protein −0.46 3156 2.11 3264 3210
LAMP2 Lysosome-associated membrane glycoprotein 2 −0.71 3369 1.64 3043 3206
BOLA2B BolA-like protein 2 −0.28 2823 3.30 3532 3177.5
PTPRF Receptor-type tyrosine-protein phosphatase F −1.03 3487 1.33 2828 3157.5
DCN Decorin −0.77 3400 1.39 2875 3137.5
AK3 GTP:AMP phosphotransferase AK3, mitochondrial −0.51 3219 1.58 3006 3112.5
HTRA1 Serine protease HTRA1 −1.47 3550 1.12 2670 3110
OGN Mimecan −0.89 3445 1.19 2731 3088
GOLIM4 Golgi integral membrane protein 4 −0.73 3379 1.25 2771 3075
LAMB2 Laminin subunit beta-2 −0.64 3331 1.29 2799 3065
ITM2B Integral membrane protein 2B −0.63 3319 1.24 2766 3042.5
SDHB Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial −0.31 2870 1.90 3175 3022.5
CST3 Cystatin-C −0.38 3034 1.51 2962 2998
LTBP4 Latent-transforming growth factor beta-binding protein 4 −0.53 3239 1.21 2745 2992
PPP3CA Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform −0.54 3245 1.15 2694 2969.5
HEXA Beta-hexosaminidase subunit alpha −0.27 2765 1.87 3163 2964
PCSK1N ProSAAS −0.83 3426 0.91 2483 2954.5