Table 1.
Summary of the cohorts used for the genome-wide association analysis (GWAS), including samples and single nucleotide polymorphisms SNPs passing quality control steps.
| Breed | Technology | AF | UF | Informative SNPs | Independent SNPs ** |
|---|---|---|---|---|---|
| Borzoi, Great Dane, GSD | WGS | 18 | 15 | 2,837,247 | 209,534 |
| Borzoi, Great Dane, GSD * | WGS | 18 | 7 | 2,794,769 | 198,090 |
| Borzoi, Great Dane, GSD | Imputed microarrays | 69 | 61 | 4,093,737 | 274,818 |
| Borzoi, Great Dane, GSD * | Imputed microarrays | 69 | 25 | 4,283,353 | 282,309 |
| All Breeds | Imputed microarrays | 125 | 90 | 4,139,410 | 399,810 |
| All Breeds * | Imputed microarrays | 125 | 45 | 4,519,848 | 434,516 |
| Borzoi | Imputed microarrays | 10 | 45 | 3,335,814 | 141,714 |
| Borzoi * | Imputed microarrays | 10 | 19 | 3,405,912 | 140,326 |
| Great Dane | Imputed microarrays | 22 | 6 | 3,612,725 | 164,347 |
| GSD | Imputed microarrays | 37 | 10 | 3,231,787 | 119,747 |
| Collie, GSP, Great Dane, | Imputed microarrays | 29 | 18 | 4,057,970 | 255,266 |
| Collie, GSP, Great Dane * | Imputed microarrays | 29 | 14 | 4,107,331 | 253,661 |
* Includes controls without GDV family history. ** Number of independent SNPs according regional LD patterns used for the multiple test adjustment of GWAS p-values. GSD: German Shepherd; GSP: German Shorthaired Pointer. AF: affected; UF: unaffected; WGS: whole genome sequencing.