Table 2.
Results of the laboratory tests and echocardiographic examinations of patients treated with apixaban, dabigatran, and rivaroxaban. The numbers are presented as the mean ± standard deviation, or numbers (percentage) otherwise mentioned. Abbreviations: eGFR, estimated glomerular filtration rate; SD, standard deviation.
| Clinical Characteristic |
all n = 2971 |
Apixaban n = 953 |
Dabigatran n = 819 |
Rivaroxaban n = 1199 |
p |
|---|---|---|---|---|---|
| Laboratory tests | |||||
| Hemoglobin Mean (SD), g/dL |
13.3 (1.8) n = 2942 | 12.8 (1.9) n = 942 | 13.5 (1.8) n = 809 |
13.5 (1.7) n = 1191 | < 0.0001 |
| White blood cell Mean (SD), K/μL |
7.9 (3.1) n = 2935 | 8.0 (2.9) n = 939 |
7.9 (3.0) n = 807 |
7.9 (3.3) n = 1189 | 0.7752 |
| Platelet Mean (SD), K/μL |
220.1 (72.7) n = 2938 | 214.4 (69.8) n = 940 | 219.5 (66.5) n = 807 | 225 (78.5) n = 1191 | 0.0032 |
| eGFR Mean (SD), ml/min/1.73m2 |
60.3 (20.2) n = 2947 |
54.1 (19.9) n = 945 |
64.1 (19.3) n = 811 |
62.6 (20.0) n = 1191 |
<0.0001 |
| eGFR < 60 mL/min/1.73m2 | 1483 (50.3) n = 2947 |
581 (61.5) n = 945 |
354 (43.6) n = 811 |
548 (46.0) n = 1191 |
<0.0001 |
| Echocardiographic findings | |||||
| Ejection fraction Mean (SD), % |
49.5 (13.3) n = 2343 | 48.0 (14.1) n = 755 | 49.4 (13.0) n = 619 | 50.7 (12.6) n = 969 | 0.0002 |
| Left atrial diameter Mean (SD), mm |
46.5 (6.8) n = 2046 | 46.6 (7.0) n = 671 | 47.0 (6.8) n = 534 |
46.2 (6.6) n = 841 | 0.0796 |
| Left ventricular systolic diameter Mean (SD), mm |
39.4 (8.6) n = 1130 | 39.0 (9.6) n = 373 | 39.5 (8.6) n = 334 |
39.8 (7.6) n = 423 | 0.4639 |
| Left ventricular diastolic diameter Mean (SD), mm |
52.5 (8.2) n = 2230 | 52.3 (8.9) n = 737 | 52.8 (7.9) n = 578 |
52.5 (7.8) n = 915 | 0.4866 |