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Schematic outline of all steps in the standardization process of p210 BCR-ABL1 transcript monitoring in patients with chronic myeloid leukemia (CML). Each laboratory uses its local assay for quantitative qRT-PCR and then expresses its results on an international scale (IS) using a conversion factor (CF) based on a reference panel (the last reference panel from 2016). Picture created with Biorender.com.
