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. 2020 Nov 6;12(11):1264. doi: 10.3390/v12111264

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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AealbAV-specific miRNAs in Ae. albopictus samples infected with CHIKV. (a) Size distribution of miRNAs mapping to the AealbAV genome (black) and antigenome (grey). (b) Mapping profiles of the 21-nt reads representing AealbAV-derived siRNAs and (c) the 27-nt reads representing AealbAV-derived piRNAs. (d) Relative nucleotide frequency and conservation of the 27-nt vpiRNAs that mapped to the genome (upper panel) and the antigenome (bottom panel) of AealbAV. AealbAV-derived vpiRNAs display the characteristic piRNA ping-pong signature with Adenine at position 10 for the genomic strand and Uridine at position 1 for the antigenomic strand.