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Synthesis of the first fragment for the Wittig reaction, deuterated heptanal as a phosphonium bromide salt (Wittig salt) (7a,b). Pimelic acid (1a,b) was used as starting material. Experimental conditions: (a) Pd(C) 10%, D2O, NaOD (40%), 260 °C, 30 bar; (b) AC2O, 150 °C; (c) CH3OH, 70 °C; (d) BH3THF; (e) CBr4 Ph3P; (f) Ph3P, CH3CN, 100 °C.
