Table 1.
Physicochemical analysis of polymer samples and low molecular weight (LMW) chitosan nanoparticles.
| Formulation | Chitosan (%) | Curcumin (µg) | Size (nm) | Zeta Potential (mV) | PDI | Drug Content (%) | Entrapment Efficiency (%) |
|---|---|---|---|---|---|---|---|
| Parent chitosan | - | - | 4123.7 ± 421.4 | 21.4 ± 2.3 | 1.0 ± 0.0 | - | - |
| LMW Chitosan | - | - | 667.7 ± 145.7 | 67.4 ± 6.2 | 0.72 ± 0.1 | - | - |
| F1 blank | 0.3 | - | 170.7 ± 2.9 | 46.4 ± 2.6 | 0.27 ± 0.05 | - | - |
| F2 blank | 0.4 | - | 223.7 ± 9.3 | 46.7 ± 1.6 | 0.5 ± 0.01 | - | - |
| F1 | 0.3 | 300 | 279.7 ± 20.3 | 52.4 ± 1.50 | 0.67 ± 0.05 | 99.99 ± 1.39 | 99.93 ± 3.43 |
| F2 | 0.4 | 400 | 259.2 ± 19.4 | 42.7 ± 1.53 | 0.54 ± 0.05 | 99.99 ± 0.34 | 99.96 ± 2.12 |