Table 1.
Top 15 features ranked by importance for each training dataset, from completely balanced (50% positive, 50% negative) to most imbalanced (5% positive, 95% negative)
| Training dataset distribution | |||||
|---|---|---|---|---|---|
| 50%–50% | 40%–60% | 30%–70% | 20%–80% | 10%–90% | 5%–95% |
| PF00698.21 | PF00698.21 | GO:0008168 | HGTGTQ | PF00109.26 | TACSSS |
| PF00668.20 | HGTGTQ | HGTGTQ | GO:0008152 | GO:0044550 | GTGTQA |
| ADGYCR | GO:0031177 | GQGAQW | PF00550.25 | LYRTGD | GYARGE |
| GO:0016491 | GAGTGG | GYCRAD | IDTACS | VFTGQG | GO:0046148 |
| FDGYRF | VEMHGT | GAGTGG | PF02458.15 | NFSAAG | TGDLAR |
| GO:0016740 | VFTGQG | QQRLLL | DTACSS | VEAHGT | SINSFG |
| MHGTGT | PF00668.20 | TACSSS | VTLSGD | GO:0043041 | DPQQRL |
| DTACSS | GO:0016874 | PF02801.22 | FTGQGA | GHSLGE | LFTSGS |
| GO:1900557 | YKTGDL | GO:0009058 | PF08242.12 | AYEALE | NSFGFG |
| GO:0009058 | GO:0019184 | GO:0046148 | AYGPTE | GO:0016491 | CDTAVA |
| GRFFAA | GO:0043042 | GO:0047462 | GO:0004315 | TQVKIR | FDASFF |
| PF14765.6 | PGRFFA | GEYAAL | GO:0031177 | GO:0046500 | AYGPTE |
| MDPQQR | MHGTGT | GO:0005829 | KLRGFR | DTACSS | YILFTS |
| FTSGST | GO:1900790 | PFAFHS | GO:0016021 | GO:0032259 | AIVLAG |
| GQGAQW | VEIGPH | LHSLEA | PF00067.22 | DTFVRC | AVVGHS |
Highlighted features appeared in multiple datasets.