Table 5.
Multiple correlation between the cumulative number of injections (median of six injections) for two years in wet AMD patients and genotypes of polymorphisms in autophagy-related genes.
Polymorphism | Genotype | R | p |
---|---|---|---|
rs2295080 | GG | 0.137 | 0.040 1 |
GT | 0.136 | 0.041 1 | |
TT | 0.088 | 0.377 | |
rs11121704 | CC | 0.089 | 0.362 |
CT | 0.099 | 0.313 | |
TT | 0.089 | 0.367 | |
rs1057079 | CC | 0.100 | 0.309 |
CT | 0.106 | 0.281 | |
TT | 0.131 | 0.049 1 | |
rs1064261 | GG | 0.093 | 0.344 |
GA | 0.129 | 0.053 | |
AA | 0.111 | 0.257 | |
rs573775 | AA | 0.083 | 0.398 |
AG | 0.105 | 0.287 | |
GG | 0.107 | 0.274 | |
rs11246867 | AA | 0.106 | 0.114 |
AG | 0.133 | 0.045 1 | |
GG | 0.106 | 0.278 | |
rs3088051 | CC | 0.148 | 0.026 1 |
CT | 0.104 | 0.290 | |
TT | 0.083 | 0.398 | |
rs73105013 | CC | ||
CT | 0.105 | 0.281 | |
TT | 0.105 | 0.281 | |
rs10277 | CC | 0.131 | 0.049 1 |
CT | 0.086 | 0.380 | |
TT | 0.087 | 0.194 | |
rs10902469 | CC | ||
CG | 0.084 | 0.391 | |
GG | 0.084 | 0.391 |
1 Bootstrapped. Adjusted to sex, age and the use of anticholesterolemic therapy. Statistically significant values are shown in bold. Cases impossible to calculate are shown by a blank row.