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. 2020 Nov 6;12(11):3294. doi: 10.3390/cancers12113294

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Oxygen-generating capacity and MR-compatibility of usNP-MnO2 under reductive and acidic conditions in vitro. (A) Pseudo-colorized oxygen saturation maps of blood containing varying concentrations of usNP-MnO₂ before (pre) and after (post) the addition of H₂O₂. (B) Bar graph shows the change in blood %sO₂ following the addition of H₂O₂ for each usNP-MnO₂ concentration. (C) Pseudocolorized T1-relaxation rate (R1) maps of usNP-MnO₂ in water at increasing concentrations before (pre) and after (post) exposure to H₂O₂. (D) Graph shows corresponding R1 measurements for each usNP-MnO₂ concentration before and after H₂O₂.