AIDS |
Acquired immunodeficiency syndrome |
WHO |
World Health Organization |
UNAIDS |
The Joint United Nations Program on HIV/AIDS |
HIV |
Human immunodeficiency virus |
HAART |
Highly active antiretroviral therapy |
ARV |
Antiretroviral |
CNS |
Central nervous system |
BBB |
Blood–brain barrier |
P-gp |
P-glycoprotein |
NLC |
Nanostructured lipid carriers |
ATZ |
Atazanavir |
SLN |
Solid lipid nanoparticle |
SNEDDS |
Self-nanoemulsifying drug delivery system |
SLB |
Solid–liquid binary lipid |
QbD |
Quality by Design |
BBD |
Box–Behnken design |
RSM |
Response surface methodology |
PDI |
Polydispersity index |
ZP |
Zeta potential |
EE |
Entrapment efficiency |
LC |
Loading capacity |
TEM |
Transmission electron microscopy |
DSC |
Differential scanning calorimetry |
PBS |
Phosphate buffer saline |
HPLC |
High performance liquid chromatographic method |
CLSM |
Confocal laser scanning microscopy |
MTT |
Methylthiazoletetrazolium |
H&E |
Hematoxylin and eosin |
CV |
Cresyl violet |
ANOVA |
Analysis of variance (ANOVA |
GRAS |
Generally recognized as safe |
HLB |
Hydrophilic–lipophilic balance |