TABLE 3.
Median reduced glutathione (GSH) values from plasma and red blood cell (RBC) hemolysates from anemic and control dogs, further divided into those with hemolytic and nonhemolytic anemia
| Plasma GSH (μM) | RBC hemolysate GSH (μM) | |||
|---|---|---|---|---|
| Median | Range | Median | Range | |
| All anemic (n = 47) | 1.9 | 0.01‐17.8 | 3.1d | 0.4‐30.8 |
| Hemolytic anemia (n = 10) | 7.6a,c | 0.4–17.8 | 2.2e | 0.4‐30.8 |
| Nonhemolytic anemia (n = 37) | 1.6a,b | 0.01–7.1 | 3.2f | 1.2‐26.4 |
| Control (n = 20) | 2.8b,c | 0.1–29.9 | 7.0d,e,f | 0.5‐29.7 |
Note: Anemic dogs had significantly lower RBC hemolysate GSH concentrations when compared to healthy dogs (P = .03). Dogs with a nonhemolytic anemia had significantly lower plasma GSH, and dogs with hemolytic anemia had significantly higher plasma GSH when compared to healthy dogs (P = .02, P = .04, respectively). Dogs with hemolytic anemia had significantly higher plasma GSH when compared to dogs with nonhemolytic anemia (P < .001). Values with matching superscript letters represent significant differences.