TABLE 1.
Descriptive data obtained from 2194 dogs with myxomatous mitral valve disease with and without atrial fibrillation (AF)
| Variable | Category | AF group, n = 59 dogs | No AF group, n = 2135 dogs | P value | ||
|---|---|---|---|---|---|---|
| Number (%), mean ± SD | Missing values, n (%) | Number (%), mean ± SD | Missing values, n (%) | |||
| Breed | Crossbred | 35 (59.3) | 817 (38.3) | .002 | ||
| Purebred | 24 (40.7) | 1318 (61.7) | ||||
| Age (mo.) | mean ± SD | 136 ± 28 | 136 ± 35 | 27 (1.3) | .69 | |
| Sex | Female | 18 (30.5) | 1141 (53.5) | 3 (0.1) | .001 | |
| Male | 41 (69.5) | 991 (46.5) | ||||
| BW (kg) | Mean ± SD | 17.3 ± 10.6 | 10.7 ± 8.6 | 11 (0.5) | <.001 | |
| HR (bpm) | Mean ± SD | 187 ± 41 | 1 (1.7) | 128 ± 31 | 5 (0.2) | <.001 |
| LA (cm) | Mean ± SD | 4.98 ± 0.97 | 1 (1.7) | 2.38 ± 0.80 | 2 (0.1) | <.001 |
| Ao (cm) | Mean ± SD | 1.91 ± 0.48 | 1 (1.7) | 1.60 ± 0.43 | 2 (0.1) | <.001 |
| LA/Ao | Mean ± SD | 2.72 ± 0.67 | 1 (1.7) | 1.52 ± 0.47 | 2 (0.1) | <.001 |
| LVDDn | Mean ± SD | 2.06 ± 0.36 | 1.55 ± 0.32 | 20 (0.9) | <.001 | |
| LVSDn | Mean ± SD | 1.26 ± 0.28 | 0.85 ± 0.23 | 22 (1.0) | <.001 | |
| FS (%) | Mean ± SD | 36.9 ± 10.4 | 43.5 ± 9.6 | 11 (0.5) | <.001 | |
| E max (m/s) | Mean ± SD | 1.49 ± 0.37 | 3 (5.1) | 0.83 ± 0.36 | 19 (0.9) | <.001 |
| PH | No | 31 (52.5) | 1638 (76.7) | <.001 | ||
| Yes | 28 (47.5) | 497 (23.3) | ||||
| ACVIM stage | B1 + B2 | 6 (10.2) | 1861 (87.2) | <.001 | ||
| C + D | 53 (89.8) | 274 (12.8) | ||||
| Treatment | CT/NT | 48 (84.8)/9 (15.8) | 263 (14.0)/1619 (86.0) | <.001 | ||
| CT/MT | 48 (100.0)/0 (0.0) | 263 (84.8)/47 (15.2) | .007 | |||
| CT/OT | 48 (96.0)/2 (4.0) | 263 (56.1)/206 (43.9) | <.001 | |||
| MT/OT | 0 (0.0)/2 (100.0) | 47 (18.6)/206 (81.4) | .81 | |||
| MT/NT | 0 (0.0)/9 (100.0) | 47 (2.8)/1619 (97.2) | .62 | |||
| NT/OT | 11 (84.6)/2 (15.4) | 206 (11.3)/1619 (88.7) | .81 | |||
Abbreviations: ACVIM, American College of Veterinary Internal Medicine; AF, atrial fibrillation; BW, body weight; CT, cardiac treatment; E max, mitral valve maximal E wave velocity; FS, fractional shortening; HR, heart rate; LA, left atrial diameter; LA/Ao, left atrial diameter to aortic diameter; LVDDn, left ventricular diastolic diameter normalized to body weight; LVSDn, left ventricular systolic diameter normalized to body weight; MT, mixed treatment; n, number of dogs; NT, no treatment; OT, other treatments; PH, pulmonary hypertension.