Figure 4.

Comparison of the Age of Onset of Depressive Disorders. The plots represent the average age of onset of each depressive disorder for the ALC and CTRL cohorts stratified for the history of chronic pain. For comparison, average age of alcohol abuse onset is also presented (last column). Abbreviations: ALC, alcohol abuse; MDE, Major Depressive Episode; MDD, Major Depressive Disorder; PDD, Persistent Depressive Disorder. * p < 0.0166, ** p < 0.0033 adjusted thresholds with Bonferroni correction for three comparisons for the three pain disorders.